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Effect of inert tablet ingredients on drug absorption I. Effect of polyethylene glycol 4000 on the intestinal absorption of four barbiturates

✍ Scribed by Leslie Z. Benet; V. N. Bhatia; Parvinder Singh; J. Keith Guillory; Theodore D. Sokoloski


Publisher
John Wiley and Sons
Year
1966
Tongue
English
Weight
563 KB
Volume
55
Category
Article
ISSN
0022-3549

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Polyethylene glycol (PEG) polymers are large amphiphilic molecules that are highly hydrated in solution. To explore the permeability properties of different sized PEG polymers across epithelial membranes in vivo, we examined the absorption of fluorescently labeled PEG conjugates sized 0.55-20 kDa fr