Effect of hypoxia and TP53 mutation status and cytogenetics of normal and malignant mammary epithelium
✍ Scribed by Hilmar Vidarsson; Margrét Steinarsdóttir; Jón Gunnlaugur Jónasson; Hildur Júlíusdóttir; Halla Hauksdóttir; Hólmfríður Hilmarsdóttir; Kristín Halldórsdóttir; Helga M. Ögmundsdóttir
- Book ID
- 113512796
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 119 KB
- Volume
- 165
- Category
- Article
- ISSN
- 0165-4608
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
In conclusion, PTEN contributes in maintaining normal cell homeostasis, and the numerous alterations found in several sporadic tumor types emphasize the significance of this tumor suppressor gene. Somatic PTEN mutations appear to play an important role in the development of a subgroup of sporadic co
## Communicated by Albert de la Chapelle PTEN regulates cell homeostasis by inhibiting growth signals transduced through PI3kinases. The gene is mutated in several cancer types, but so far, only a limited number of mutations have been reported in colorectal cancer. In the present study, direct seq
## Abstract Oncogenic mutations in the __KRAS2__, __NRAS__, or __FLT3__ gene are detected in more than 50% of patients with de novo acute myeloid leukemia (AML). __RAS__ mutations are also prevalent in de novo myelodysplastic syndrome (MDS), especially chronic myelomonocytic leukemia and juvenile m