To investigate the role of the p53 tumor-suppressor gene in the development of human melanoma, loss of heterozygosity (LOH) of p53 was studied in 46 cases of melanoma by a polymerase-chain-reaction/restriction-fragment-len~h polymorphism (PCR/RFLP) analysis, and p53 mutations were assessed in 5 I ca
Point mutations and allelic loss in the TP53 locus of cutaneous malignant melanomas
β Scribed by J. Weiss; W. K. Cavenee; R. A. Herbst; E. G. Jung; K. C. Arden
- Book ID
- 104745621
- Publisher
- Springer-Verlag
- Year
- 1994
- Tongue
- English
- Weight
- 267 KB
- Volume
- 286
- Category
- Article
- ISSN
- 0340-3696
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