𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effect of host sex and splenectomy on moloney virus-induced sarcomas

✍ Scribed by Sylvia B. Pollack

Publisher
John Wiley and Sons
Year
1971
Tongue
French
Weight
448 KB
Volume
8
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Female BALB/c mice injected intramuscularly with Moloney sarcoma virus (MSV) developed tumors which were smaller and were rejected more quickly than those induced in age‐matched males. Tumor rejection was also more frequent in splenectomized hosts than in sham‐operated controls. The eject of splenectomy was more pronounced in females than in males.

In sub‐lethally irradiated mice challenged with MSV, sex‐related and spleen‐dependent differences in response to adoptively transferred spleen cells were observed. In females, both splenectomized and sham‐operated recipients of immune cells rejected their primary sarcomas, while the tumors grew rapidly in all recipients of normal cells. In a concurrent experiment with males, splenectomy had a greater suppressive effect on tumor growth than did the type of spleen cells tranferred (immune vs. normal).

📜 SIMILAR VOLUMES

Inhibitory effects of xenogeneic antiser
Inhibitory effects of xenogeneic antiserum on the growth of Moloney virus-induced sarcomas
✍ Dr. George E. Pierce 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 347 KB

## Abstract An antiserum was developed in rabbits by injections of a virus concentrate from Moloney murine sarcomas. Passive transfer of this antiserum attenuated the growth of both primary and transplanted Moloney murine sarcomas. It also facilitated tumor regression and increased survival times o

Enhanced growth of primary moloney virus
Enhanced growth of primary moloney virus-induced sarcomas in mice
✍ George E. Pierce 📂 Article 📅 1971 🏛 John Wiley and Sons 🌐 French ⚖ 675 KB

## Abstract Pre‐treatment of BALB/c mice with an intraperitoneal injection of heat‐inactivated serum obtained from BALB/c mice with progressively growing Moloney‐virus‐induced sarcomas (“progressor” mice) shortens the latent period and increases the growth rate and maximum size of primary sarcomas

Kinetics of inflammation and sarcoma cel
Kinetics of inflammation and sarcoma cell development in primary moloney sarcoma-virus-induced tumors
✍ Susanne Becker; Stephen Haskill 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 597 KB

## Abstract The kinetics of ‘sarcoma’ cell appearance and inflammatory cell infiltration into primary Moloney sarcoma virus (MSV)‐induced tumors has been studied in normal and partially immunosuppressed anti‐lymphocyte‐globulin (ALG)‐treated A/WySn mice. The ALG treatment facilitated an earlier app

Further studies on mouse sarcoma virus (
Further studies on mouse sarcoma virus (moloney) replication in human cells. Partial host range shift of progeny virus
✍ C. Bernard; J. C. Chuat; I. Laprevotte; M. Boiron 📂 Article 📅 1972 🏛 John Wiley and Sons 🌐 French ⚖ 736 KB

## Abstract Several human cell lines were examined for their susceptibility to infection by mouse sarcoma virus, strain Moloney (M‐MSV). Successful transformation was achieved only with concentrated virus from rat cell line 78 Al. The lag time and the extent of cellular alteration were found to be

Effect of anti-mouse type-1 interferon g
Effect of anti-mouse type-1 interferon globulin on the evolution of moloney sarcoma virus induced disease in mice
✍ Anna D. Inglot; Olga Inglot; Albina Zóltowska; Emilia Oleszak 📂 Article 📅 1979 🏛 John Wiley and Sons 🌐 French ⚖ 437 KB

## Abstract The prolonged administration of potent sheep anti‐mouse type‐1 interferon globulin (anti‐IF IgG) had a marked potentiating effect on Moloney sarcoma virus (MSV) infection in mice. The extent of resistance to the MSV‐induced disease was age‐related. In 4‐week‐old BALB/c mice, anti‐IF IgG

Structure and expression of mos sequence
Structure and expression of mos sequences in spontaneous and moloney murine sarcoma virus-induced yolk sac carcinomas in rats
✍ B. Decock; H. Sobis; L. Van Hove; M. Vandeputte; A. Billiau 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 French ⚖ 990 KB

Facilitation of yolk-sac carcinoma (YSCa) development in fetectomized rats by the Moloney murine sarcoma virus/murine leukemia virus (Mo-MSV/MLV) complex was found to be closely associated with the presence of Mo-MSV sequences in the genomes of the YSCa cells. The virus-induced YSCas consisted of ce