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Effect of growth temperature on the formation of sister-chromatid exchanges in BrdUrd-substituted chromosomes

✍ Scribed by C. Gutiérrez; J.B. Schvartzman; J.F. López-Sáez

Book ID
115891473
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
584 KB
Volume
134
Category
Article
ISSN
0014-4827

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Sister chromatid exchanges (SCEs) are induced in cultured Chinese hamster cells by treatment with 5-bromodeoxyuridine (BrdU) or with Hoechst 33258 (H33258) plus BrdU. The SCE frequencies depend upon the number of H33258 molecules available per cell (or per base pair) and the number of brdU molecules