Effect of endothelium mimicking self-assembled nanomatrices on cell adhesion and spreading of human endothelial cells and smooth muscle cells
β Scribed by Adinarayana Andukuri; Will P. Minor; Meenakshi Kushwaha; Joel M. Anderson; Ho-Wook Jun
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 907 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1549-9634
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Endothelial cells (ECs) and smooth muscle cells (SMCs), which are the major component cells of blood vessels, produce various bioactive substances and communicate with each other through them. Although several studies of the interaction between ECs and SMCs have been reported, the eect of coculture
## Abstract In this work, we demonstrate that surface charge can be used to modulate cell adhesion/spreading through the control of the orientation of adsorbed FnIII~7β10~, which is a cellβadhesive protein containing RGD residues. Carboxylic acid (COOH) and amine (NH~2~)βterminated selfβassembled m