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Effect of drugs used in combined electroanesthesia and ataralgesia on the appearance of hepatospecific enzymes in the blood

✍ Scribed by M. I. Kuzin; M. Ya. Avrutskii; A. A. Karelin; N. V. Babkina; R. N. Korotkina; B. M. Shloznikov; A. V. Machulin


Publisher
Springer US
Year
1987
Tongue
English
Weight
228 KB
Volume
104
Category
Article
ISSN
0007-4888

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✍ Maria Nord; Peter Zsigmond; Anita Kullman; Kerstin Γ…rstrand; Nil Dizdar πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 75 KB

## Abstract Levodopa combined with a dopa‐decarboxylase inhibitor, such as carbidopa, shifts the metabolism to the COMT pathway. Adding the peripheral acting COMT inhibitor entacapone provides improvement for patients with PD suffering from motor fluctuations. We studied the effects of the enzyme i