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Effect of drug vehicles on N-demethylase activity in isolated hepatocytes

✍ Scribed by Marion E. Sauers; Robert T. Abraham; John D. Alvin; Michael A. Zemaitis


Book ID
115775323
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
408 KB
Volume
29
Category
Article
ISSN
0006-2952

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Barbiturate N-demethylase activity in is
✍ Robert T. Abraham; Marion E. Sauers; Michael A. Zemaitis; John D. Alvin πŸ“‚ Article πŸ“… 1983 πŸ› Elsevier Science 🌐 English βš– 817 KB

The isolated hepatocyte preparation has become an increasingly popular system for studying xenobiotic metabolism, and there is a need for methods of determining metabolic activity. Described here is a simple and sensitive radiometric assay for barbiturate iV-demethylase activity in the isolated hepa