## Abstract Proflavine binding may be used as a probe of the environment and interactions of DNA. In this paper we report the effects of the divalent cations Mg^++^ and putrescine and the trivalent cation spermidine on the proflavineβNa DNA binding equilibrium. Difference spectroscopy at 430 nm was
Effect of DNA base composition on the intercalation of proflavine: A kinetic study
β Scribed by J. Ramstein; M. Leng
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- English
- Weight
- 734 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0301-4622
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The dependence of the net hydration of DNA on it,s base composition has been measured by density gradient ultrncentrifugation of three 1)l"u'A's in a series of cesium and lithium salt solutions of different water aativiticxs. 1t;strapolation to zero water activity showed the tkyeridcucc of thc parti
We utilize the dynamic quenching of the triplet state of methylene blue by molecular oxygen to observe changes in the rate at which oxygen can penetrate the helix as a function of base-pair composition. The results indicate that the interior of the oligonucleotide dAdT is more accessible than dGdC t
## Abstract The kinetics of interaction between proflavine and poly I.poly C at 25Β°C, neutral pH, and moderate ionic strength have been studied by relaxation methods. The qualitative features of this system resemble those previously reported by Crothers and coβworkers for proflavineβDNA and proflav