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Effect of dissolved oxygen concentration onnarpromoter activity in batch and semi-continuous cultivations

✍ Scribed by Eock Kee Hong; Kwang Soo Kim


Book ID
105661447
Publisher
The Korean Society for Biotechnology and Bioengineering
Year
1999
Tongue
English
Weight
462 KB
Volume
4
Category
Article
ISSN
1226-8372

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Oxygen transport is a major limitation in large-scale mammalian cell culture. The effects of the dissolved oxygen concentration (DO; from 0.1 to 100% saturation with air) on Sp2/0-derived mouse hybridomas were investigated using continuous culture. The steady-state concentration of viable cells incr