Effects of dissolved oxygen concentratio
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William M. Miller; Charles R. Wilke; Harvey W. Blanch
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Article
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1987
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John Wiley and Sons
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English
β 725 KB
Oxygen transport is a major limitation in large-scale mammalian cell culture. The effects of the dissolved oxygen concentration (DO; from 0.1 to 100% saturation with air) on Sp2/0-derived mouse hybridomas were investigated using continuous culture. The steady-state concentration of viable cells incr