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Effect of Cyclic Nucleotides, Isoproterenol and Cholera Toxin on DNA Synthesis Triggered by Mitogens

✍ Scribed by M. EMIN; S. DUBISKI; B. CINADER


Book ID
110860268
Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
530 KB
Volume
8
Category
Article
ISSN
0300-9475

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The effect of sodium orthovanadate on enhancement of DNA synthesis by T and B cell mitogenic agents was studied using murine thymocytes and splenocytes. Addition of vanadate to thymocyte cultures inhibited the mitogenic response induced by concanavalin A in a dose dependent manner (50% inhibition at