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Effect of culture conditions on the utilization of precursors in the biosynthesis of penicillin

✍ Scribed by T. P. Verkhovtseva; L. M. Lur'e; M. M. Levitov

Book ID
112404733
Publisher
Springer
Year
1973
Tongue
English
Weight
149 KB
Volume
7
Category
Article
ISSN
0091-150X

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Penicillin V acylase was produced, both intracellularly and extracellularly, by Fusarium sp. SKF 235 grown in submerged fermentation. When neopeptone was added to the medium, >95% of the penicillin V acylase was extracellular. In the absence of a complex organic nitrogen source, the fungus produced