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Utilization of side-chain precursors for penicillin biosynthesis in a high-producing strain ofPenicillium chrysogenum

✍ Scribed by Susanne Havn Eriksen, Bo Jensen, Ib Schneider…


Book ID
120768053
Publisher
Springer
Year
1994
Tongue
English
Weight
541 KB
Volume
40
Category
Article
ISSN
1432-0614

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The isopenicillin N synthase (pcbC) and acyl-CoA:6-APA acyltransferase (penDE) genes of Penicillium chrysogenum were located in a 19.5-kb DNA fragment that had been previously cloned in phage vector EMBL3. This 19.5-kb DNA fragment was mapped with several endonucleases, and the pcbC and penDE genes