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Effect of copper(II) chloride on suppression of racemization in peptide synthesis by the mixed anhydride and related methods

โœ Scribed by MIYAZAWA, TOSHIFUMI ;DONKAI, TOMOKO ;YAMADA, TAKASHI ;KUWATA, SHIGERU


Book ID
115099293
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
418 KB
Volume
40
Category
Article
ISSN
0367-8377

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Copper(II) chloride as a new, efficient
โœ Toshifumi Miyazawa; Toshihiko Otomatsu; Takashi Yamada; Shigeru Kuwata ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 142 KB

Copper chloride was found to be an extremely efficient additive suppressing racemization in the carbodiimide mediated couplings. The use of additives in the dicyclohexylcarbodiimide (DCC) method is an important improvement contributing to the suppression of racemization in segment couplings. Among a