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Effect of compound GB-115 on morphine-induced analgesia

✍ Scribed by L. G. Kolik; V. N. Zhukov; S. B. Seredenin


Book ID
106357599
Publisher
Springer US
Year
2007
Tongue
English
Weight
307 KB
Volume
143
Category
Article
ISSN
0007-4888

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The analgesic effect of morphine in a mouse writhing assay was enhanced by the simultaneous administration of fluoxetine, an inhibitor of serotonin uptake. Fluoxetine reduced the ED, for morphine and extended the duration of morphine analgesia. The potentiation of morphine analgesia was particularly