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Effect of cephaloridine on human chromosomes in vitro in lymphocyte cultures

✍ Scribed by Manjula Jaju; Madhuri Jaju; Y.R. Ahuja

Book ID
119092497
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
350 KB
Volume
101
Category
Article
ISSN
0165-1218

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In this study the clastogenic effect of pyrimethamine (Daraprim), a folic acid antagonist used for the treatment of toxoplasmosis and malaria on human chromosomes, was investigated. Pyrimethamine was added to in vitro lymphocyte cultures at six different concentrations: 0.05 (normal therapeutic dose