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Effect of apolipoprotein E polymorphism on bile lipid composition and the formation of cholesterol gallstone

✍ Scribed by Kiyoshi Hasegawa; Sachiyo Terada; Keiichi Kubota; Hiroshige Itakura; Hiroshi Imamura; Shin Ohnishi; Taku Aoki; Masayoshi Ijichi; Akio Saiura; Masatoshi Makuuchi

Book ID
119394133
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
77 KB
Volume
98
Category
Article
ISSN
0002-9270

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In five patients with radiolucent gallstones, the effect of ursodeoxycholic acid (Urso) in doses of 250,500, 750, 1,000, and 1,250 mg per day on biliary lipid and bile acid composition was studied. Biliary cholesterol decreased from 8.8 f 0.8 mole% to 4.4 f 0.2 mole% at 500 mg Urso per day (7.1 mg p