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Effect of aminoglutethimide on antipyrine, theophylline, and digitoxin disposition in breast cancer

✍ Scribed by Lønning, Per E; Kvinnsland, Stener; Bakke, Olav M


Book ID
109843514
Publisher
Nature Publishing Group
Year
1984
Tongue
English
Weight
368 KB
Volume
36
Category
Article
ISSN
0009-9236

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On the basis of reports that some calcium channel blockers impair the elimination of some drugs, the effect of nifedipine on the disposition of antipyrine and theophylline was assessed in healthy volunteers. Antipyrine half-life of 10.04 f 1.43 h (mean f SD) after a week intake of nifedipine (20 mg