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Effect of oral high-dose progestins on the disposition of antipyrine, digitoxin, and warfarin in patients with advanced breast cancer

✍ Scribed by Steinar Lundgren; Stener Kvinnsland; Edle Utaaker; Olav Bakke; Magne Ueland


Publisher
Springer
Year
1986
Tongue
English
Weight
538 KB
Volume
18
Category
Article
ISSN
0344-5704

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The influence of a graded dose schedule
✍ P. E. LΓΈnning; P. M. Ueland; S. Kvinnsland πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 508 KB

The pharmacokinetics of the optical enantiomers of warfarin (R-warfarin and S-warfarin) were investigated in patients treated for breast cancer with aminoglutethimide (AG). The patients received 125 mg AG b.i.d. (i.e., low-dosage regimen); 250 mg AG q.i.d. together with cortisone acetate (i.e. high-