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Effect of age on the association between polymorphism of the p16INK4A in head and neck carcinoma and patient survival


Book ID
119336268
Publisher
Elsevier
Year
2012
Tongue
English
Weight
54 KB
Volume
114
Category
Article
ISSN
2212-4403

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## Abstract Both p53 tumor suppressor and murine double minute 2 (MDM2) oncoprotein are crucial in carcinogenesis. We hypothesized that __MDM2__ promoter single nucleotide polymorphisms (SNPs) SNP309 T > G, A2164G, and __p53__ codon 72 are associated with risk and age at onset of squamous cell carc