Effect of aceclidine on scopolamine- and electroshock-induced amnesia in rats
β Scribed by M. D. Mashkovskii; V. A. Parshin; R. B. Parimbetova
- Publisher
- Springer US
- Year
- 1997
- Tongue
- English
- Weight
- 285 KB
- Volume
- 123
- Category
- Article
- ISSN
- 0007-4888
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Scopolamine (3 mg/kg IP) given before an acquisition trial, reduced the retention of a one-trial passive avoidance "step through" response in mice. A single administration of cholinergic agonists such as oxotremorine, BM-5, or arecoline, antagonized this amnesic effect of scopolamine. A significant
The effects of Fructus Schisandrae (Schizandra Chinensis, (FS) on cycloheximide (CXM)-induced amnesia by using a passive avoidance task were studied in rats. FS at 0.25 and 0.75 g/kg administered for 1 week significantly prolonged the CXM-shortened step-through latency (STL). Of the fractions (n-hex