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Effects of Fructus schizandrae on cycloheximide-induced amnesia in rats

✍ Scribed by Dr Ming-Tsuen Hsieh; Meng-Lin Tsai; Wen-Huang Peng; Chi-Rei Wu


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
38 KB
Volume
13
Category
Article
ISSN
0951-418X

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✦ Synopsis


The effects of Fructus Schisandrae (Schizandra Chinensis, (FS) on cycloheximide (CXM)-induced amnesia by using a passive avoidance task were studied in rats. FS at 0.25 and 0.75 g/kg administered for 1 week significantly prolonged the CXM-shortened step-through latency (STL). Of the fractions (n-hexane, chloroform and water), only the water fraction at 25 mg/kg administered for 1 week prolonged the CXM-shortened STL. These results suggest that the water fraction is the main active fraction of FS.


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