Effects of Fructus schizandrae on cycloheximide-induced amnesia in rats
β Scribed by Dr Ming-Tsuen Hsieh; Meng-Lin Tsai; Wen-Huang Peng; Chi-Rei Wu
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 38 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0951-418X
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β¦ Synopsis
The effects of Fructus Schisandrae (Schizandra Chinensis, (FS) on cycloheximide (CXM)-induced amnesia by using a passive avoidance task were studied in rats. FS at 0.25 and 0.75 g/kg administered for 1 week significantly prolonged the CXM-shortened step-through latency (STL). Of the fractions (n-hexane, chloroform and water), only the water fraction at 25 mg/kg administered for 1 week prolonged the CXM-shortened STL. These results suggest that the water fraction is the main active fraction of FS.
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