Effect of 24,25(OH)2D3 on PTH levels and bone histology in dogs with chronic uremia
โ Scribed by Olgaard, Klaus; Finco, Delmar; Schwartz, John; Arbelaez, Mario; Teitelbaum, Steven; Avioli, Louis; Klahr, Saulo; Slatopolsky, Eduardo
- Book ID
- 109879308
- Publisher
- Nature Publishing Group
- Year
- 1984
- Tongue
- English
- Weight
- 680 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0085-2538
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Resting zone chondrocyte differentiation is modulated by the vitamin D metabolite, 24,25-(OH) 2 D 3 , via activation of protein kinase C (PKC). In previous studies, inhibition of prostaglandin production with indomethacin caused an increase in PKC activity, suggesting that changes in prostaglandin l