Effect of 1,25(OH)2D3and 24,25(OH)2D3on calcium ion fluxes in costochondral chondrocyte cultures
โ Scribed by G. G. Langston; L. D. Swain; Z. Schwartz; F. Del Toro; R. Gomez; Barbara D. Boyan
- Book ID
- 110554619
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 682 KB
- Volume
- 47
- Category
- Article
- ISSN
- 1432-0827
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Prior studies have shown that 24,25-(OH) 2 D 3 and 1,25-(OH) 2 D 3 regulate protein kinase C (PKC) in costochondral chondrocytes in a cell maturation-dependent manner, with 1,25-(OH) 2 D 3 affecting primarily growth zone (GC) cells and 24,25-(OH) 2 D 3 affecting primarily resting zone (RC) cells. In
We have previously reported an absence of a 1,25(OH)2D3-mediated effect on 45Ca handling by intestinal epithelial cells isolated from normal chicks (Nemere and Campbell [2000] Steroids 65:451-457). In the current work, we provide evidence that in similar cell preparations, 1,25(OH)2D3 increased 32P