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Effects of phosphate and 1,25(OH)2D3on in vitro bone collagen synthesis in the hypophosphatemic mouse

โœ Scribed by Brigitte Ecarot-Charrier; Francis H. Glorieux

Publisher
Springer
Year
1983
Tongue
English
Weight
734 KB
Volume
35
Category
Article
ISSN
1432-0827

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๐Ÿ“œ SIMILAR VOLUMES

Abnormal modulation of serum osteocalcin
Abnormal modulation of serum osteocalcin by dietary phosphate and 1,25-dihydroxyvitamin D3 in the hypophosphatemic mouse
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We evaluated in normal and hypophosphatemic (Hyp) mice whether changes in serum levels of osteocalcin in response to dietary phosphate supplementation, parathyroid hormone (PTH) and 1,25-dihydroxyvitamin D, (1,25(OH),D,) administration were related to perturbations in calcium phosphate homeostasis.

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We have previously reported an absence of a 1,25(OH)2D3-mediated effect on 45Ca handling by intestinal epithelial cells isolated from normal chicks (Nemere and Campbell [2000] Steroids 65:451-457). In the current work, we provide evidence that in similar cell preparations, 1,25(OH)2D3 increased 32P