The effect of a single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 10 microgram . kg-1, on the status of vitamin A (retinol) was studied in rats during an eight week period after administration. Retinol was determined spectrophotometrically after separation by means of high pressure liq
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the hepatic storage of retinol in rats with different dietary supplies of vitamin A (retinol)
✍ Scribed by Tuula Thunberg; Ulf G. Ahlborg; Helen Håkansson; Cilla Krantz; Mats Monier
- Publisher
- Springer-Verlag
- Year
- 1980
- Tongue
- English
- Weight
- 735 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0340-5761
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This study aimed to clarify the effects of single and repeated administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the activities or expression of some metabolic enzymes of retinoids and the influence of supplemental vitamin A on changed vitamin A homeostasis by TCDD. In Experiment I, th
The distribution of iron, copper, zinc, and magnesium in hepatic subcellular fractions of male and female rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was determined. Animals received 40 micrograms TCDD per kilogram per day for three days by mouth (po) or the vehicle and were killed