Editorial: NMR Spectroscopy of Biomacromolecules in Drug Discovery and Beyond

[Methods and Principles in Medicinal Che

[Methods and Principles in Medicinal Chemistry] Fragmentâbased Approaches in Drug Discovery || Synergistic Use of Protein Crystallography and Solutionâphase NMR Spectroscopy in Structureâbased Drug Design: Strategies and Tactics

✍ Jahnke, Wolfgang; Erlanson, Daniel A. 📂 Article 📅 2006 🏛 Wiley ⚖ 303 KB 👁 1 views

Diagnosis of a case of acute chloroquine

Diagnosis of a case of acute chloroquine poisoning using 1H NMR spectroscopy: characterisation of drug metabolites in urine

✍ Susanna Maschke; Nathalie Azaroual; Jean-Michel Wieruszeski; Guy Lippens; Michel 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 245 KB 👁 1 views

Analysis of biological fluids by proton nuclear magnetic resonance spectroscopy ( 1 H NMR) is a promising tool in clinical biology. We have used this method for a rapid toxicological screening in the case of a suicide attempt. A urine sample was analysed at 300 and 600 MHz by 1D and 2D sequences (J-

Isolation of circulating metabolites in

Isolation of circulating metabolites in drug discovery using high-performance liquid chromatography, and their identification by liquid chromatography coupled with tandem mass spectrometry and nuclear magnetic resonance spectroscopy

✍ Hong Kim; Wenqing Feng; Tze-Ming Chan; Diane Rindgen; Matthew Bryant; Kathleen A 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 221 KB 👁 3 views

Isolation of circulating metabolites in drug discovery using high-performance liquid chromatography, and their identification by liquid chromatography coupled with tandem mass spectrometry and nuclear magnetic resonance spectroscopy One of the major components of modern drug discovery is the structu

[Methods and Principles in Medicinal Che

[Methods and Principles in Medicinal Chemistry] Fragmentâbased Approaches in Drug Discovery || SAR by NMR: An Analysis of Potency Gains Realized Through Fragmentâlinking and Fragmentâelaboration Strategies for Lead Generation

✍ Jahnke, Wolfgang; Erlanson, Daniel A. 📂 Article 📅 2006 🏛 Wiley ⚖ 344 KB 👁 1 views