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EBV-negative Hodgkin lymphoma in ZAP-70-positive B-cell lymphocytic leukemia patient

✍ Scribed by Jan Cerny; Sa Wang; Patricia Miron; Lloyd Hutchinson; Doreen Brettler

Book ID
105989264
Publisher
Springer
Year
2008
Tongue
English
Weight
233 KB
Volume
88
Category
Article
ISSN
0939-5555

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## Abstract ## Background: Zeta‐chain associated protein of 70kDa (ZAP‐70) is the most promising surrogate marker for the immunoglobulin heavy chain variable region (IgV~H~) mutation status in B‐cell chronic lymphocytic leukemia (B‐CLL). Crespo et al. proposed the detection of ZAP‐70 by flow cytom