𝔖 Bobbio Scriptorium
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Easy access to the epothilone family-synthesis of epothilone B

✍ Scribed by Johann Mulzer; Andreas Mantoulidis; Elisabeth Öhler

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
197 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis

An easy access to four out of five naturally occurring epothilones (A-E, 1-5) is reported. Key steps are an enantioselective Mukaiyama type aldol reaction, (E)-and (Z)-selective olefinations, and a sulfone alkylation.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of Epothi
ChemInform Abstract: Synthesis of Epothilones: Stereoselective Routes to Epothilone B.
✍ D. SCHINZER; A. BAUER; J. SCHIEBER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 25 KB 👁 1 views

## Synthesis of Epothilones: Stereoselective Routes to Epothilone B. -In continuation of studies concerning the total synthesis of epothilones, efficient routes to epothilone B (I) using a macro-lactonization and a metathesis approach are detailed.

ChemInform Abstract: Easy Access to Both
ChemInform Abstract: Easy Access to Both Enantiomers of C7—C12 Segment of Epothilones.
✍ Shinji Tanimori; Koichi Tanimoto; Mitsunori Kirihata 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 27 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v