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Early steps of the conformational change of influenza virus hemagglutinin to a fusion active state: Stability and energetics of the hemagglutinin

✍ Scribed by Qiang Huang; Rachakonda P. Sivaramakrishna; Kai Ludwig; Thomas Korte; Christoph Böttcher; Andreas Herrmann

Book ID
117048282
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
694 KB
Volume
1614
Category
Article
ISSN
0005-2736

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✍ Thomas Korte; Andreas Herrmann 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 977 KB

Binding of the fluorophore 1,1'-bis(4-anilino)naphthalene-5,5'-disulfonic acid (bis-ANS) to influenza virus A/PR 8/34 is strongly enhanced at low pH. Binding is accompanied by a significant increase in fluorescence intensity. The binding and the fluorescence increase are associated with the low-pH i