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A Histidine Residue of the Influenza Virus Hemagglutinin Controls the pH Dependence of the Conformational Change Mediating Membrane Fusion

โœ Scribed by Mair, C. M.; Meyer, T.; Schneider, K.; Huang, Q.; Veit, M.; Herrmann, A.

Book ID
127296650
Publisher
American Society for Microbiology
Year
2014
Tongue
English
Weight
670 KB
Volume
88
Category
Article
ISSN
0022-538X

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โœ Thomas Korte; Andreas Herrmann ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Springer ๐ŸŒ English โš– 977 KB

Binding of the fluorophore 1,1'-bis(4-anilino)naphthalene-5,5'-disulfonic acid (bis-ANS) to influenza virus A/PR 8/34 is strongly enhanced at low pH. Binding is accompanied by a significant increase in fluorescence intensity. The binding and the fluorescence increase are associated with the low-pH i