Dequalinium induces cell death in human
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Pilar Sancho; Eva Galeano; Elena Nieto; M. Dolores Delgado; Ana Isabel García-Pé
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Article
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2007
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Elsevier Science
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English
⚖ 732 KB
Dequalinium (DQA) has been proposed as a selective antitumoral agent due to its preferential accumulation in mitochondria of cancer cells. Our aim was a better understanding of DQA cytotoxicity. DQA-induced NB4 and K562 cell alterations are initiated within the first 30 min of treatment at a high DQ