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Mitochondrial involvement in cell death

✍ Scribed by Sten Orrenius; Erik Norberg; Vladimir Gogvadze; Boris Zhivotovsky


Book ID
116925022
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
42 KB
Volume
211
Category
Article
ISSN
0378-4274

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## Abstract Oligodendrocytes, the myelin‐forming cells of the CNS, are specifically sensitive to oxidative stress and respond by the onset of programmed cell death (PCD). To further unravel the molecular events underlying their enhanced susceptibility, we have investigated whether mitochondrial dam