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Early inhibition of succinic dehydrogenase by manganese in Rat Gonads

✍ Scribed by Raushan Husain; Prahlad K. Seth; Satya V. Chandra


Book ID
112606700
Publisher
Springer
Year
1976
Tongue
English
Weight
171 KB
Volume
16
Category
Article
ISSN
0007-4861

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Brain succinate dehydrogenase (SDH) activity was inhibited by in vitro hexachlorophene (HCP) with a half inhibitory concentration (IC 50 ) of 0.65 ‫‬ 10 ‫3‬ M. The HCP exerted noncompetitive inhibition at 0.5 mM (Ο½IC 50 ), uncompetitive inhibition at 0.65 mM (IC 50 ), and mixed-type inhibition at 0.