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Early age of onset in fatal familial insomnia

✍ Scribed by A. Harder*; A. Gregor*; T. Wirth; F. Kreuz; W. J. Schulz-Schaeffer; O. Windl; M. Plotkin; H. Amthauer; K. Neukirch; H. A.. Kretzschmar; T. Kuhlmann; R. Braas; H. H. Hahne; K. Jendroska


Publisher
Springer
Year
2004
Tongue
English
Weight
368 KB
Volume
251
Category
Article
ISSN
0340-5354

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## Abstract The effect of the apolipoprotein E (APOE) Ο΅4 allele on age of onset was analyzed in two groups of families with early‐onset Alzheimer's disease (AD), (1) Volga German (VG) kindreds, in which AD is caused by an unknown locus and (2) early‐onset non‐VG families showing evidence of linkage