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e6-a2 BCR-ABL1 fusion in T-cell acute lymphoblastic leukemia

✍ Scribed by Quentmeier, H; Cools, J; MacLeod, R A F; Marynen, P; Uphoff, C C; Drexler, H G


Book ID
110056118
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
118 KB
Volume
19
Category
Article
ISSN
0887-6924

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## Abstract T‐cell acute lymphoblastic leukemia (T‐ALL) is the result of multiple oncogenic insults of thymocytes. Recently, new __ABL1__ fusion genes have been identified that provide proliferation and survival advantage to lymphoblasts. These are the __NUP214‐ABL1__ fusion gene, on amplified epis