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E-Cadherin germline mutations and risk of gastric cancer

✍ Scribed by Kenneth E.L. McColl; Emad El-Omar


Book ID
119756782
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
65 KB
Volume
123
Category
Article
ISSN
0016-5085

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πŸ“œ SIMILAR VOLUMES


E-cadherin germline mutations define an
✍ Guilford, Parry J. (author);Hopkins, Justin B.W. (author);Grady, William M. (aut πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 287 KB πŸ‘ 1 views

## Communicated by Henrik Dahl To extend earlier observations of germline E-cadherin mutations in kindreds with an inherited susceptibility to diffuse gastric cancer, we searched for germline E-cadherin mutations in five further families affected predominantly by diffuse gastric cancer and one fami

Screening E-cadherin in gastric cancer f
✍ Carla Oliveira; Maria Cristina Bordin; Nicola Grehan; David Huntsman; Gianpaolo πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 429 KB

The International Gastric Cancer Linkage Consortium (IGCLC) predicted that up to 25% of families fulfilling the criteria for hereditary diffuse gastric cancer (HDGC) would harbor CDH1 germline mutations. This was based on observations from the low number of diffuse gastric cancer families described

Germline mutations in E-cadherin do not
✍ BjΓΆrn-Anders Jonsson; Anders Bergh; PΓ€r Stattin; Monika Emmanuelsson; Henrik GrΓΆ πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 French βš– 273 KB

## Abstract Somatic mutations in the __E‐cadherin__ (__CDH1__) gene have frequently been reported in cases with diffuse gastric and lobular breast cancers. Recently, germline mutations have been identified in families with diffuse gastric cancers. In families with hereditary prostate cancer (HPC),