E-cadherin germline mutations in familial gastric cancer
β Scribed by Guilford, Parry; Hopkins, Justin; Harraway, James; McLeod, Maybelle; McLeod, Ngahiraka; Harawira, Pauline; Taite, Huriana; Scoular, Robin; Miller, Andrew; Reeve, Anthony E.
- Book ID
- 109750447
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 337 KB
- Volume
- 392
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/32918
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The International Gastric Cancer Linkage Consortium (IGCLC) predicted that up to 25% of families fulfilling the criteria for hereditary diffuse gastric cancer (HDGC) would harbor CDH1 germline mutations. This was based on observations from the low number of diffuse gastric cancer families described
## Abstract Germline mutations in __MSH2__, __MLH1__, __Eβcadherin__ and __MutY__ (__MYH__) genes have been implicated in the occurrence of gastric cancer (GC). Epidemiological investigation was performed by recruiting patients with GC onset during 2002 in Jiangsu province, China. We identified sus
## Communicated by Henrik Dahl To extend earlier observations of germline E-cadherin mutations in kindreds with an inherited susceptibility to diffuse gastric cancer, we searched for germline E-cadherin mutations in five further families affected predominantly by diffuse gastric cancer and one fami