## Abstract 3‐__O__‐benzyl (and 3‐__O__‐methyl)‐1,2‐__O__‐isopropylidene‐α‐D‐__xylo__‐dialdo‐1,4‐furanoses treated with bromocyanomethylidene‐ or bromoacylmethylidene‐triphenylphosphoranes gave in good yields the corresponding olefinic sugars. These compounds, which bear three adjacent electrophili
Dérivés C-glycosyliques X. C-Nucléosides oxadiazoliques inversés. Communication préliminaire
✍ Scribed by J. M. J. Tronchet; R. E. Moskalyk
- Publisher
- John Wiley and Sons
- Year
- 1972
- Tongue
- German
- Weight
- 228 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
The synthesis of «reversed» 1, 3, 4‐oxadiazolyl C‐nucleosides by treatment of alduronic chlorides with N‐benzoylamino‐triphenylphosphinimine or by oxidation of __aldehydo__dialdose benzoylphenylhydrazones is described. One of these compounds is the first example of an «reversed» C‐amino‐nucleoside having a β‐heteroaryl‐ethylamino grouping, a structural unit whose introduction into a sugar molecule is interesting from a pharmacological standpoint.
📜 SIMILAR VOLUMES
## Abstract 1,2‐O‐Isopropylidene‐3‐O‐methyl‐α‐D‐__xylo__‐pentodialdo‐1,4‐furanose and its 3‐O‐benzyl analog have been reacted with pyridinyl‐3‐methylenetriphenylphosphorane and benzimidazolyl‐2‐methylenetriphenylphosphorane. The unsaturated sugars so obtained are vinylogs of homo‐C‐glycosides whose
## Abstract Treated with 2,3‐dimethyl‐2,3‐bis‐(hydroxylamino)‐butane, aldehydo‐dialdofuranoses (**1**) gave a mixture of two compounds: a 1,3‐dihydroxyimidazolidine (**2**) and a 1‐hydroxyimidazoline (**3**). Oxidation (PbO~2~) of compounds **3** gave stable free radicals having the structure of 2‐
**C‐Glycosylic derivatives XXXII. Synthesis of __spiro__‐C‐glycosylidenic derivatives __via__ nucleophilic cyclization.** On treatment with compounds bearing two nucleophilic groups as ethylenediamine, __o__‐phenylenediamine or their monooxa or monothia analogues, 1,2:5, 6‐di‐__O__‐isopropylidene‐α
**Diglycosyl Derivatives. Preliminary communication** Novel types of diglycosyl compounds, some of them bearing a resemblance to natural di‐ or tri‐saccharides are described: a diglycosyldiyne (**1**), a diglycosylthiophene (**2**), a diglycosylaziridine (**3**), a diglycosyldioxolane (**4**), as w
## Abstract The syntheses of three types of sugar nitrones (aldonitrone, ketonitrone and α‐β unsaturated aldonitrone) are described. On 1,3‐dipolar cycloaddition with phenylacetylene, the aldonitrone gave two Δ~4~‐isoxazolines epimeric at the new asymetric carbon, while the same reaction on the ket