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Dystrophin-positive myotubes in innervated muscle cultures from Duchenne and Becker muscular dystrophy patients

โœ Scribed by Fanin, M.; Hoffman, E.P.; Saad, F.A.; Martinuzzi, A.; Danieli, G.A.; Angelini, C.


Book ID
122440219
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
736 KB
Volume
3
Category
Article
ISSN
0960-8966

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## Communicated by Ulf Landegren Duchenne and Becker muscular dystrophy (DMD and BMD) are caused by mutations in the dystrophin gene. Large rearrangements in the gene are found in about two-thirds of DMD patients, with B60% carrying deletions and 5-10% carrying duplications. Most of the remaining