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Proportion and pattern of dystrophin gene deletions in North Indian Duchenne and Becker muscular dystrophy patients

โœ Scribed by Vinita Singh; Shirish Sinha; Sudhish Mishra; Lakshmi Shankar Chaturvedi; Sunil Pradhan; R. D. Mittal; B. Mittal


Publisher
Springer
Year
1997
Tongue
English
Weight
25 KB
Volume
99
Category
Article
ISSN
0340-6717

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## Communicated by Ulf Landegren Duchenne and Becker muscular dystrophy (DMD and BMD) are caused by mutations in the dystrophin gene. Large rearrangements in the gene are found in about two-thirds of DMD patients, with B60% carrying deletions and 5-10% carrying duplications. Most of the remaining