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Dystrophin expression in the mdx mouse restored by stem cell transplantation

✍ Scribed by Gussoni, Emanuela; Soneoka, Yuko; Strickland, Corinne D.; Buzney, Elizabeth A.; Khan, Mohamed K.; Flint, Alan F.; Kunkel, Louis M.; Mulligan, Richard C.

Book ID
115453401
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
284 KB
Volume
401
Category
Article
ISSN
0028-0836

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## Abstract ## Background Duchenne and Becker muscular dystrophies are allelic disorders arising from mutations in the dystrophin gene. Duchenne muscular dystrophy is characterised by an absence of functional protein, while Becker muscular dystrophy is usually caused by in‐frame deletions allowing