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Restoration of dystrophin expression in mdx mice by intravascular injection of naked DNA containing full-length dystrophin cDNA

✍ Scribed by Liang, K W; Nishikawa, M; Liu, F; Sun, B; Ye, Q; Huang, L


Book ID
110039532
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
256 KB
Volume
11
Category
Article
ISSN
0969-7128

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## Abstract We showed that a __LacZ__ expression plasmid (pCAG‐lacZ) injection followed by electroporation increased the expression of the __LacZ__ gene in the skeletal muscles of adult __mdx__ mice up to ninefold higher as compared with simple intramuscular DNA injection. When full‐length mouse dy