✦ LIBER ✦

Enhanced in vivo delivery of antisense oligonucleotides to restore dystrophin expression in adult mdx mouse muscle

✍ Scribed by K.E. Wells; S. Fletcher; C.J. Mann; S.D. Wilton; D.J. Wells

Book ID: 117105740
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 336 KB
Volume: 552
Category: Article
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(03)00904-9

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

T.P.2.10 Restoration of dystrophin expre

T.P.2.10 Restoration of dystrophin expression in mdx mouse by peptide-conjugated antisense oligonucleotides

✍ H.F. Yin; Y.Q. Seow; H.M. Moulton; P.L. Iversen; J.K. Boutilier; M.J.A. Wood 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 46 KB

In vivo delivery of naked antisense olig

In vivo delivery of naked antisense oligos in aged mdx mice: Analysis of dystrophin restoration in skeletal and cardiac muscle

✍ Libero Vitiello; Nicola Bassi; Paola Campagnolo; Eva Zaccariotto; Gianluca Occhi 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 719 KB

T.P.2.08 Dystrophin expression after sys

T.P.2.08 Dystrophin expression after systemic delivery of morpholino antisense oligonucleotide in mdx mouse: A dose–response analysis

✍ A. Malerba; G. Dickson; I. Graham 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 45 KB

Dystrophin expression in the mdx mouse a

Dystrophin expression in the mdx mouse after localised and systemic administration of a morpholino antisense oligonucleotide

✍ Susan Fletcher; Kaite Honeyman; Abbie M. Fall; Penny L. Harding; Russell D. John 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 494 KB

## Abstract ## Background Duchenne and Becker muscular dystrophies are allelic disorders arising from mutations in the dystrophin gene. Duchenne muscular dystrophy is characterised by an absence of functional protein, while Becker muscular dystrophy is usually caused by in‐frame deletions allowing

Intraperitoneal administration of phosph

Intraperitoneal administration of phosphorothioate antisense oligodeoxynucleotide against splicing enhancer sequence induced exon skipping in dystrophin mRNA expressed in mdx skeletal muscle

✍ Yasuhiro Takeshima; Mariko Yagi; Hiroko Wada; Masafumi Matsuo 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 162 KB

Towards a therapeutic inhibition of dyst

Towards a therapeutic inhibition of dystrophin exon 23 splicing in mdx mouse muscle induced by antisense oligoribonucleotides (splicomers): target sequence optimisation using oligonucleotide arrays

✍ Ian R. Graham; Vanessa J. Hill; Muthiah Manoharan; Gopal B. Inamati; George Dick 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 424 KB

## Abstract ## Background The activity of synthetic antisense oligonucleotides (splicomers) designed to block pre‐mRNA splicing at specific exons has been demonstrated in a number of model systems, including constitutively spliced exons in mouse dystrophin RNA. Splicomer reagents directed to Duche