Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application
β Scribed by Muhammad Furqan, Nikhil Mukhi, Byung Lee, Delong Liu
- Book ID
- 119915165
- Publisher
- BioMed Central
- Year
- 2013
- Tongue
- English
- Weight
- 290 KB
- Volume
- 1
- Category
- Article
- ISSN
- 2050-7771
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## Abstract __unpaired__ (__upd__) encodes a ligand for the Jak/STAT signaling pathway in __Drosophila__. In the second instar and early third larval eye disc, __upd__ is expressed in the center of the posterior margin. __upd__ lossβofβfunction mutations caused eye size reduction and __upd__ overex