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Targeting the Interleukin-6/Jak/Stat Pathway in Human Malignancies

✍ Scribed by Sansone, P.; Bromberg, J.

Book ID
111950234
Publisher
American Society of Clinical Oncology
Year
2012
Tongue
English
Weight
526 KB
Volume
30
Category
Article
ISSN
0732-183X

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## Abstract ## Objective S100A4 has been shown to be increased in osteoarthritic (OA) cartilage and to stimulate chondrocytes to produce matrix metalloproteinase 13 (MMP‐13) through activation of the receptor for advanced glycation end products (RAGE). The aim of this study was to examine the mech