Dysplastic cells in cytological cervical samples show a high incidence of chromosomal abnormalities
β Scribed by Minghao Song; Adam Ruth; Frank A. Policht; Lukas Bubendorf; Georg Feichter; Benjamin R. Kipp; Kevin C. Halling; Irina A. Sokolova
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 135 KB
- Volume
- 38
- Category
- Article
- ISSN
- 8755-1039
- DOI
- 10.1002/dc.21142
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π SIMILAR VOLUMES
BACKGROUND. Some cervical/vaginal Papanicolaou (Pap) smears previously diagnosed as normal in women with a high grade squamous intraepithelial lesion (HSIL) are found to contain abnormal cells on retrospective review. This study characterized and quantitated such cells in 100 Pap smears. ## METHODS
## Abstract This report describes the appearance of ectopic chromosome around centrosome (ECAC) in metaphase cell nuclei of highβrisk HPVβassociated cervical neoplasms. ECAC are clearly visible on HEβstained sections as a tiny (approx. 0.7 ΞΌ), round, dark structure or an aggregate of filamentous ch