Dyskeratosis congenita: a genetic disord
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M Kirwan; I Dokal
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Article
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2007
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John Wiley and Sons
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English
β 529 KB
Dyskeratosis congenita (DC) is an inherited syndrome exhibiting marked clinical and genetic heterogeneity. It is characterized by multiple features including mucocutaneous abnormalities, bone marrow failure and an increased predisposition to cancer. Three genetic subtypes are recognized: Xβlinked re