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Dyskeratosis Congenita: A Disorder of Defective Telomere Maintenance?

✍ Scribed by Amanda J. Walne; Anna Marrone; Inderjeet Dokal


Book ID
111835473
Publisher
Carden Jennings Publishing
Year
2005
Tongue
English
Weight
131 KB
Volume
82
Category
Article
ISSN
0925-5710

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Dyskeratosis congenita: a genetic disord
✍ M Kirwan; I Dokal πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 529 KB

Dyskeratosis congenita (DC) is an inherited syndrome exhibiting marked clinical and genetic heterogeneity. It is characterized by multiple features including mucocutaneous abnormalities, bone marrow failure and an increased predisposition to cancer. Three genetic subtypes are recognized: X‐linked re