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The genetics of dyskeratosis congenita

✍ Scribed by Philip J. Mason; Monica Bessler


Book ID
116332645
Publisher
Elsevier
Year
2011
Tongue
English
Weight
409 KB
Volume
204
Category
Article
ISSN
2210-7762

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Dyskeratosis congenita: a genetic disord
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Dyskeratosis congenita (DC) is an inherited syndrome exhibiting marked clinical and genetic heterogeneity. It is characterized by multiple features including mucocutaneous abnormalities, bone marrow failure and an increased predisposition to cancer. Three genetic subtypes are recognized: X‐linked re